Endocrine Abstracts

The classical diagnostic strategy of internal medicine, including medical history, physical examination and additional diagnostic test, is unable to assess the activity of the autonomous nervous system in detail and, consequently, has resulted in negligence of the involvement of the autonomic nervous system. Nonetheless, evidence is emerging that the autonomous nervous system is involved in the pathophysiology of complex diseases. These conditions include insulin resistance, t...

Growth hormone deficiency frequently occurs as consequence of radiation therapy in pituitary disorders. However, it not known whether radiation therapy in acromegaly results in comparable diminution of GH secretion. We therefore hypothesized that stimulated and spontaneous GH release is ultimately indistinguishable in irradiated acromegalic patients and irradiated patients with other pituitary disorders. For this study 10 acromegalic patients and 10 patients with other pituita...